We are interested in discovering the pathways through which stress can affect the biology of a child. Our study will measure how stress associates with a number of biological markers, such as stress hormones, (hair and salivary cortisol and aldosterone), epigenetic markers at stress-related genes (DNA methylation), blood pressure, and BMI in both mothers and children. We predict that stress may become embedded in the biology to predispose children to develop cardiovascular or metabolic diseases in adulthood.
We are also measuring genetic ancestry of each child to share geneaologic history with the families, and to adjust for population stratification in our analyses.
CHICOS teammembers in training
For results of phase 1 focus groups, see
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